Voltage-dependent anion channel in mammalian spermatozoa.

Liu B, Zhang W, Wang Z.

Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Abstract

Voltage-dependent anion channel (VDAC) is a multi-functional channel protein in the mitochondrial outer membrane of all eukaryotes. It is involved in extensive physiological and pathophysiological processes. However there is only scant information about VDAC in mammalian reproduction, fertility and development in the past. It is now recognized through recent studies that VDAC is present in male mammalian germinal tissues and cells, and plays crucial roles in spermatogenesis, sperm maturation and fertilization. This review will discuss the presence, localization and function of VDAC in mammalian spermatozoa. 江苏省人民医院泌尿外科王增军

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发布时间:2011-01-30 18:38

王增军主任医师教授

江苏省人民医院泌尿外科

擅长：肾癌前列腺癌膀胱癌的诊治，男性不育性功能障碍的诊治；机器人辅助腹腔镜下复杂性泌尿生殖系统肿瘤如肾癌根治及保留肾单位肾部分切除术，保留性神经膀胱癌根治性切除原位新膀胱术，保留性神经及尿控功能前列腺癌根治术，睾丸癌腹膜后淋巴结清扫等微创治疗，尿道断裂尿道修复重建手术，泌尿生殖系统先天性畸形如肾盂输尿管连接部狭窄和小儿尿道下裂修复重建等。前列腺增生症微创治疗，男性勃起功能障碍假体植入，血精的微创治疗，男性不育（少弱精及无精子症）的诊治等。 << 收起

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